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Bus from Panama City, FL to Sanford, NC

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Bus stations and stops in Panama City, FL

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Frequently asked questions

The travel time from Panama City to Sanford by bus is approximately 21 hours 35 minutes, covering a distance of about 773 miles. The fastest route includes .
Bus tickets from Panama City to Sanford start at $111.99. To get the best deals, book your tickets in advance through our app or website. Payment options include debit or credit cards online, or cash at certain locations.
You can check the status of your Greyhound bus traveling from Panama City to Sanford by using our bus tracker. This tool provides real-time updates on your bus’s location and expected arrival time.
For your trip from Panama City to Sanford, Greyhound allows one carry-on bag (max 25 lbs, 16x12x7 inches) and one checked bag under the bus at no extra charge. A second checked bag is free with a Flexible fare. You can add extra baggage during booking or later via "Manage My Booking," or at certain locations. Full details are on our baggage policy page.
Traveling by Greyhound from Panama City to Sanford is an environmentally friendly option, helping to reduce carbon emissions and traffic congestion compared to car travel.
On Greyhound buses from Panama City to Sanford, you can enjoy free Wi-Fi, power outlets at each seat, comfortable reclining seats with extra legroom, overhead storage, and access to an onboard restroom.
The earliest bus from Panama City to Sanford departs at 12:50 pm.
The latest bus from Panama City to Sanford leaves at 12:50 pm.
Yes, you can book both Greyhound and FlixBus tickets for travel from Panama City to Sanford on our website. Simply enter your travel details to compare schedules and fares.
There are up to one Greyhound bus operating daily from Panama City to Sanford. Check the schedule by entering your travel date in the search box above.
Greyhound offers wheelchair lifts and space for passengers using mobility devices. It is recommended to book your trip from Panama City to Sanford in advance. Service animals are welcome on all Greyhound buses. For more information, visit our accessibility page.
The locations of Greyhound bus stops in Panama City and Sanford can be found on this page, along with detailed maps and addresses.

Planning Your Greyhound Bus Trip from Panama City to Sanford?

The journey from Panama City to Sanford can take as little as 21 hours 35 minutes and starts from as little as $111.99. The earliest bus leaves at 12:50 pm. Greyhound provides daily buses Panama City to Sanford from Panama City to Sanford. Travel with Greyhound and enjoy complimentary Wifi, access to power sockets, and a comfortable seat throughout your trip. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to Sanford in seconds.

How to Book Your Bus Ticket to Sanford from Panama City

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Panama City to Sanford, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Sanford, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability