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Bus from Knoxville, TN to Ithaca, NY

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Bus stations and stops in Knoxville, TN

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Frequently asked questions

There are up to one Greyhound bus operating daily from Knoxville to Ithaca. Check the schedule by entering your travel date in the search box above.
The travel time from Knoxville to Ithaca by bus is approximately 22 hours 25 minutes, covering a distance of about 978 miles. The fastest route includes .
You can check the status of your Greyhound bus traveling from Knoxville to Ithaca by using our bus tracker. This tool provides real-time updates on your bus’s location and expected arrival time.
For your trip from Knoxville to Ithaca, Greyhound allows one carry-on bag (max 25 lbs, 16x12x7 inches) and one checked bag under the bus at no extra charge. A second checked bag is free with a Flexible fare. You can add extra baggage during booking or later via "Manage My Booking," or at certain locations. Full details are on our baggage policy page.
Traveling by Greyhound from Knoxville to Ithaca is an environmentally friendly option, helping to reduce carbon emissions and traffic congestion compared to car travel.
On Greyhound buses from Knoxville to Ithaca, you can enjoy free Wi-Fi, power outlets at each seat, comfortable reclining seats with extra legroom, overhead storage, and access to an onboard restroom.
The earliest bus from Knoxville to Ithaca departs at 10:50 pm.
The latest bus from Knoxville to Ithaca leaves at 10:50 pm.
Yes, you can book both Greyhound and FlixBus tickets for travel from Knoxville to Ithaca on our website. Simply enter your travel details to compare schedules and fares.
Greyhound offers wheelchair lifts and space for passengers using mobility devices. It is recommended to book your trip from Knoxville to Ithaca in advance. Service animals are welcome on all Greyhound buses. For more information, visit our accessibility page.
The locations of Greyhound bus stops in Knoxville and Ithaca can be found on this page, along with detailed maps and addresses.

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How to Book Your Bus Trip to Ithaca from Knoxville

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Knoxville to Ithaca, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Ithaca, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability