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Bus from San Francisco, CA to Portsmouth, NH

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Bus stations and stops in San Francisco, CA

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Frequently asked questions

Greyhound buses from San Francisco to Portsmouth offer free Wi-Fi, power outlets at each seat, reclining seats with extra legroom, overhead storage, and onboard restrooms.
You can find the bus stops for Greyhound in both San Francisco and Portsmouth by viewing the map on this page, which includes addresses and locations of all stops.
Greyhound buses are equipped with wheelchair lifts and spaces for passengers using mobility devices. We recommend booking your trip from San Francisco to Portsmouth in advance. Service animals are welcome on all Greyhound buses. For more information, please visit our accessibility page.
There are up to one daily Greyhound bus trip from San Francisco to Portsmouth. Use the search tool above to check the schedule.
Yes, you can book tickets for both Greyhound and FlixBus from San Francisco to Portsmouth on our website. After entering your travel details, you can compare schedules and fares for both options.
The last bus from San Francisco to Portsmouth departs at 11:25 pm.
The first bus from San Francisco to Portsmouth departs at 5:30 pm.
Choosing Greyhound for your journey from San Francisco to Portsmouth is an eco-conscious option, helping to reduce emissions and traffic compared to traveling by car.
For your trip from San Francisco to Portsmouth, Greyhound allows one carry-on bag (up to 25 lbs, 16x12x7 inches) and one checked bag for free. If you have a Flexible fare, you can also check a second bag at no additional cost. Extra or oversized baggage can be added during booking or later via "Manage My Booking." Certain locations allow in-person payment for extra luggage. More details are available on our baggage policy page
To track your Greyhound bus from San Francisco to Portsmouth, use our bus tracker. It provides real-time updates on your bus’s location and expected arrival times.
A bus ticket from San Francisco to Portsmouth starts at $280.99. For the cheapest rates, it’s best to book in advance through our app or website. You can pay online with a debit or credit card, or in cash at select locations.
The Greyhound bus ride from San Francisco to Portsmouth takes around 92 hours 25 minutes, covering a distance of approximately 3651 miles. The fastest route involves .

Looking for Greyhound Bus Tickets from San Francisco to Portsmouth?

Your search ends here! We've got all the info you need to plan your bus journey. The trip from San Francisco to Portsmouth can be as quick as 92 hours 25 minutes and as cost-effective as $280.99. The first bus of the day departs at 5:30 pm and the last bus departs at 11:25 pm. Greyhound runs daily buses San Francisco to Portsmouth between San Francisco and Portsmouth. Traveling with Greyhound guarantees free Wifi, access to power sockets, and a guaranteed seat for your journey. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to Portsmouth in seconds.

How to Book Your Bus Trip to Portsmouth from San Francisco

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from San Francisco to Portsmouth, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Portsmouth, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability