Bus from Orange County-Anaheim-Santa Ana, CA to San Diego, CA

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Bus stations and stops in Orange County-Anaheim-Santa Ana, CA

Please note: your ticket will contain the most up-to-date address information.

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Frequently asked questions

With Greyhound, you can travel from Orange County-Anaheim-Santa Ana to San Diego for as little as $19.98. On average, tickets for this route cost around $28.48.
The bus route from Orange County-Anaheim-Santa Ana to San Diego covers 77 miles.
With Greyhound you can travel from Orange County-Anaheim-Santa Ana to San Diego in 1 hour 10 minutes.
To find the next available bus from Orange County-Anaheim-Santa Ana to San Diego, just enter your travel date in the search bar above to view departure times and ticket options.
Yes, there are 8 buses running every day from Orange County-Anaheim-Santa Ana to San Diego.
You can pay for your bus ticket from Orange County-Anaheim-Santa Ana to San Diego using your preferred method — including credit card, PayPal, Google Pay and cash.
You can check the real-time status and location of your bus from Orange County-Anaheim-Santa Ana to San Diego using our Bus Tracker.
Yes, overnight bus options are available from Orange County-Anaheim-Santa Ana to San Diego. With modern onboard amenities, Greyhound offers one of the most comfortable ways to travel at night.
With Greyhound, you can conveniently reach 32 destinations from San Diego, including Los Angeles, Orange County-Anaheim-Santa Ana, Long Beach.
If you want to bring your bike with you on Greyhound between Orange County-Anaheim-Santa Ana and San Diego, you can. Transport options and prices are subject to availability.
The first bus from Orange County-Anaheim-Santa Ana to San Diego departs at 7:10 am.
The last bus from Orange County-Anaheim-Santa Ana to San Diego departs at 10:05 pm.
There are 3 Greyhound bus stops in Orange County-Anaheim-Santa Ana. You can find the location of the stops on the map on this page.
There are 5 Greyhound bus stops in San Diego. You can find the location of the stops on the map on this page.

Bus Travel Summary: Orange County-Anaheim-Santa Ana to San Diego with Greyhound

  • Travel distance: The bus journey from Orange County-Anaheim-Santa Ana to San Diego covers approximately 77 miles, depending on the specific route.
  • Trip duration: The average bus ride with Greyhound from Orange County-Anaheim-Santa Ana to San Diego takes around 1 hour 10 minutes, depending on traffic and route conditions.
  • Bus schedule: To view upcoming Greyhound departures, simply enter your travel date and check the next available bus from Orange County-Anaheim-Santa Ana to San Diego.
  • Daily bus departures: 8 buses run from Orange County-Anaheim-Santa Ana to San Diego every day.
  • Night service: Overnight buses are available between Orange County-Anaheim-Santa Ana and San Diego, offering a restful and efficient travel option.
  • Greyhound stops in Orange County-Anaheim-Santa Ana: 3 stops are available, including: Anaheim Regional Transportation Intermodal Center, Irvine (Crawford Hall - University of California, Irvine), Santa Ana Bus Stop
  • Greyhound stops in San Diego: 5 stops are served, including: San Diego (Downtown/Seaport Village), San Diego (La Jolla - UC San Diego), San Diego (Old Town-FlixBus), San Diego Greyhound Bus Stop, San Diego State University (Hardy Ave)

Bus Ticket Booking

  • Bus ticket price: Greyhound bus tickets from Orange County-Anaheim-Santa Ana to San Diego start at $19.98 (average fare: $28.48.
  • Booking: Book your Orange County-Anaheim-Santa Ana to San Diego bus ticket online through this website or the free Greyhound app for the best selection and fares.
  • Payment: Choose your preferred payment method from secure options like credit card, PayPal, or Google Pay during checkout.

Seating Options

  • Standard seat: Included at no extra cost and automatically assigned when you book your Greyhound trip from Orange County-Anaheim-Santa Ana to San Diego.
  • Seat reservation: Prefer a specific seat or extra legroom? You can reserve one for an additional fee based on the seat type.

Baggage Information

When travelling with Greyhound, your ticket includes 2 pieces of baggage at no extra cost:

  • Carry-on baggage: 1 small bag (up to 25 lb / 12'×7'×16') - must fit under the seat or overhead. Keep valuables with you during your Orange County-Anaheim-Santa Ana–San Diego journey.
  • Checked baggage: 1 larger bag (up to 50 lb / 20'×12'×31') - stowed in the luggage compartment before boarding in Orange County-Anaheim-Santa Ana.

Onboard Accessibility with Greyhound

  • Priority seating: Reserved seats are available for passengers with disabilities near the front of the bus.
  • Mobility assistance: Drivers and staff can help with boarding, baggage, and mobility devices - just ask at each stage of your journey.
  • Service animals: ADA-recognised service animals are welcome on board.
  • More info: Full accessibility guidelines are available on our Accessibility Help Page.

Onboard services are subject to availability