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Bus from Florence, SC to Charlotte, NC

More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

On this page

Bus stations and stops in Florence, SC

Please note: your ticket will contain the most up-to-date address information.
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Frequently asked questions

With Greyhound, you can travel from Florence to Charlotte for as little as $41.98. On average, tickets for this route cost around $47.98.
The bus route from Florence to Charlotte covers 168 miles.
With Greyhound you can travel from Florence to Charlotte in 3 hours 50 minutes.
To find the next available bus from Florence to Charlotte, just enter your travel date in the search bar above to view departure times and ticket options.
Yes, there are 2 buses running every day from Florence to Charlotte.
You can pay for your bus ticket from Florence to Charlotte using your preferred method — including credit card, PayPal, Google Pay and cash.
You can check the real-time status and location of your bus from Florence to Charlotte using our Bus Tracker.
With Greyhound, you can conveniently reach 56 destinations from Charlotte, including Atlanta, Washington, New York.
If you want to bring your bike with you on Greyhound between Florence and Charlotte, you can. Transport options and prices are subject to availability.
The first bus from Florence to Charlotte departs at 12:05 am.
The last bus from Florence to Charlotte departs at 4:15 pm.
There are 2 Greyhound bus stops in Florence. You can find the location of the stops on the map on this page.
There are 2 Greyhound bus stops in Charlotte. You can find the location of the stops on the map on this page.

Bus Travel Summary: Florence to Charlotte with Greyhound

  • Travel distance: The bus journey from Florence to Charlotte covers approximately 168 miles, depending on the specific route.
  • Trip duration: The average bus ride with Greyhound from Florence to Charlotte takes around 3 hours 50 minutes, depending on traffic and route conditions.
  • Bus schedule: To view upcoming Greyhound departures, simply enter your travel date and check the next available bus from Florence to Charlotte.
  • Daily bus departures: 2 buses run from Florence to Charlotte every day.
  • Greyhound stops in Florence: 2 stops are available, including: Florence (SC), Florence Bus Station
  • Greyhound stops in Charlotte: 2 stops are served, including: Charlotte (Freedom Dr/Ashley Rd), Charlotte Bus Station

Bus Ticket Booking

  • Bus ticket price: Greyhound bus tickets from Florence to Charlotte start at $41.98 (average fare: $47.98.
  • Booking: Book your Florence to Charlotte bus ticket online through this website or the free Greyhound app for the best selection and fares.
  • Payment: Choose your preferred payment method from secure options like credit card, PayPal, or Google Pay during checkout.

Seating Options

  • Standard seat: Included at no extra cost and automatically assigned when you book your Greyhound trip from Florence to Charlotte.
  • Seat reservation: Prefer a specific seat or extra legroom? You can reserve one for an additional fee based on the seat type.

Baggage Information

When travelling with Greyhound, your ticket includes 2 pieces of baggage at no extra cost:

  • Carry-on baggage: 1 small bag (up to 25 lb / 12'×7'×16') - must fit under the seat or overhead. Keep valuables with you during your Florence–Charlotte journey.
  • Checked baggage: 1 larger bag (up to 50 lb / 20'×12'×31') - stowed in the luggage compartment before boarding in Florence.

Onboard Accessibility with Greyhound

  • Priority seating: Reserved seats are available for passengers with disabilities near the front of the bus.
  • Mobility assistance: Drivers and staff can help with boarding, baggage, and mobility devices - just ask at each stage of your journey.
  • Service animals: ADA-recognised service animals are welcome on board.
  • More info: Full accessibility guidelines are available on our Accessibility Help Page.

Onboard services are subject to availability