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Bus from Lake City, FL to Indianapolis, IN

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Bus stations and stops in Lake City, FL

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Frequently asked questions

There are up to 3 Greyhound buses operating daily from Lake City to Indianapolis. Check the schedule by entering your travel date in the search box above.
The travel time from Lake City to Indianapolis by bus is approximately 18 hours 30 minutes, covering a distance of about 837 miles. The fastest route includes .
You can check the status of your Greyhound bus traveling from Lake City to Indianapolis by using our bus tracker. This tool provides real-time updates on your bus’s location and expected arrival time.
For your trip from Lake City to Indianapolis, Greyhound allows one carry-on bag (max 25 lbs, 16x12x7 inches) and one checked bag under the bus at no extra charge. A second checked bag is free with a Flexible fare. You can add extra baggage during booking or later via "Manage My Booking," or at certain locations. Full details are on our baggage policy page.
Traveling by Greyhound from Lake City to Indianapolis is an environmentally friendly option, helping to reduce carbon emissions and traffic congestion compared to car travel.
On Greyhound buses from Lake City to Indianapolis, you can enjoy free Wi-Fi, power outlets at each seat, comfortable reclining seats with extra legroom, overhead storage, and access to an onboard restroom.
The earliest bus from Lake City to Indianapolis departs at 9:35 am.
The latest bus from Lake City to Indianapolis leaves at 7:20 pm.
Yes, you can book both Greyhound and FlixBus tickets for travel from Lake City to Indianapolis on our website. Simply enter your travel details to compare schedules and fares.
Greyhound offers wheelchair lifts and space for passengers using mobility devices. It is recommended to book your trip from Lake City to Indianapolis in advance. Service animals are welcome on all Greyhound buses. For more information, visit our accessibility page.
The locations of Greyhound bus stops in Lake City and Indianapolis can be found on this page, along with detailed maps and addresses.

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How to Book Your Bus Trip to Indianapolis from Lake City

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Lake City to Indianapolis, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Indianapolis, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Onboard services are subject to availability