Bus from Lake City, FL to Panama City, FL

More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Explore now

Enjoy free onboard entertainment

Watch a FREE movie and use our power outlets to stay powered up during your trip.

Find out what’s playing

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Window or Aisle?

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

Discover all your options

Bus stations and stops in Lake City, FL

Please note: your ticket will contain the most up-to-date address information.

Lake City Bus Station

251 S Marion Ave
Lake City, FL 32025
United States

View this address on Google Maps

The bus will board in front of the building where there are three zones facing the building

To view more info about this station, visit our page Lake City Bus Station

Discover all the places you can go

Choose from almost 2,300 destinations with Greyhound, FlixBus and our connecting partners!

Lake City, FL - Panama City, FL: Quick information

Online payment

Yes

Distance

180 miles

Direct connection

Yes

Frequently asked questions

How long does the bus from Lake City to Panama City take with Greyhound?

The journey by Greyhound bus from Lake City to Panama City covers approximately 215 miles. The quickest trip duration is 4 hours, with at least 3 stops.

How much is the bus from Lake City to Panama City and how can I buy a ticket?

Bus tickets from Lake City to Panama City start at $36.99. For the best rates, it is recommended to book in advance via our app or website. You can pay online using debit or credit cards, or choose to pay in person with cash at selected locations.

How do I track my Greyhound bus from Lake City to Panama City ?

To track your bus from Lake City to Panama City, use Greyhound’s bus tracker. This tool provides live updates on the bus’s location and expected arrival times.

How much baggage can I bring on the bus from Lake City to Panama City?

When traveling from Lake City to Panama City with Greyhound, you can bring one carry-on bag (up to 25 lbs, 16x12x7 inches) for free. Additionally, one checked bag is included, with a second bag free for Flexible fare passengers. Extra or oversized baggage can be added during booking or later through the "Manage My Booking" section. Some locations also allow in-person payment for additional luggage. Full details are available on our baggage policy page.

Is traveling with Greyhound from Lake City to Panama City environmentally-friendly?

Opting for Greyhound to travel from Lake City to Panama City is an environmentally responsible choice, reducing traffic and lowering emissions compared to car travel.

What onboard services are available on Greyhound buses from Lake City to Panama City?

Onboard amenities on Greyhound buses from Lake City to Panama City include free Wi-Fi, personal power outlets, reclining seats with extra legroom, overhead storage, and an onboard restroom.

What time is the first bus from Lake City to Panama City?

The first Greyhound bus from Lake City to Panama City departs at 9:40 am.

What time is the last bus from Lake City to Panama City?

The last Greyhound bus from Lake City to Panama City leaves at 9:40 am.

Can I book bus tickets both for Greyhound and FlixBus to travel from Lake City to Panama City?

Yes, you can book both Greyhound and FlixBus tickets for travel from Lake City to Panama City through our website. After selecting your cities and travel dates, you can compare the schedules and prices of both services.

How many daily Greyhound bus trips are there from Lake City to Panama City?

Greyhound operates up to 1 trip daily from Lake City to Panama City. You can find the schedule by entering your departure date in the search box above.

What facilities does Greyhound provide for passengers with reduced mobility and service animals?

Greyhound buses are equipped with wheelchair lifts and have space for two passengers using wheelchairs or mobility scooters. We recommend booking your trip from Lake City to Panama City in advance to secure the necessary accommodations. Service animals are also welcome on all Greyhound buses. For more details, visit our accessibility page.

Where are the Greyhound bus stops in Lake City and in Panama City?

You can find the Greyhound bus stops in both Lake City and Panama City by checking the map on this page, which shows the addresses and locations of all stops.

Planning Your Greyhound Bus Trip from Lake City to Panama City?

The journey from Lake City to Panama City can take as little as 4 hours and starts from as little as $36.99. The earliest bus leaves at 9:40 am. Greyhound provides daily buses Lake City to Panama City from Lake City to Panama City. Travel with Greyhound and enjoy complimentary Wifi, access to power sockets, and a comfortable seat throughout your trip. Don't miss any updates on your bus trip: stay informed with our real-time bus tracker and check the status of your ride to Panama City in seconds.

How to Book Your Bus Ticket to Panama City from Lake City

With Greyhound, reserving a ticket for your bus trip is a breeze. You can easily complete your booking on this website or through the free Greyhound App, all within a few simple clicks. You will have a variety of rides to choose from, as on many of our routes you will be offered both Greyhound and FlixBus bus rides, so you can choose the option that best fits your schedule. When booking your ticket from Lake City to Panama City, you have a range of secure online payment options at your disposal, including both debit and credit cards. If you prefer, cash payments are also accepted at various sales points. If you're on the hunt for a cheap ticket to Panama City, remember to book early. Traveling on weekdays or during non-peak hours can also lead you to some of the most budget-friendly fares available!

Discover more popular bus connections

Onboard services are subject to availability