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Bus from Lake City, FL to Orlando, FL

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You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.
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Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.
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Bus stations and stops in Lake City, FL

Please note: your ticket will contain the most up-to-date address information.

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Frequently asked questions

Opting for Greyhound to travel from Lake City to Orlando is an environmentally responsible choice, reducing traffic and lowering emissions compared to car travel.
Onboard amenities on Greyhound buses from Lake City to Orlando include free Wi-Fi, personal power outlets, reclining seats with extra legroom, overhead storage, and an onboard restroom.
The first Greyhound bus from Lake City to Orlando departs at 1:55 pm.
The last Greyhound bus from Lake City to Orlando leaves at 7:20 pm.
Yes, you can book both Greyhound and FlixBus tickets for travel from Lake City to Orlando through our website. After selecting your cities and travel dates, you can compare the schedules and prices of both services.
Greyhound operates up to 2 trips daily from Lake City to Orlando. You can find the schedule by entering your departure date in the search box above.
Greyhound buses are equipped with wheelchair lifts and have space for two passengers using wheelchairs or mobility scooters. We recommend booking your trip from Lake City to Orlando in advance to secure the necessary accommodations. Service animals are also welcome on all Greyhound buses. For more details, visit our accessibility page.
You can find the Greyhound bus stops in both Lake City and Orlando by checking the map on this page, which shows the addresses and locations of all stops.
When traveling from Lake City to Orlando with Greyhound, you can bring one carry-on bag (up to 25 lbs, 16x12x7 inches) for free. Additionally, one checked bag is included, with a second bag free for Flexible fare passengers. Extra or oversized baggage can be added during booking or later through the "Manage My Booking" section. Some locations also allow in-person payment for additional luggage. Full details are available on our baggage policy page.
The journey by Greyhound bus from Lake City to Orlando covers approximately 152 miles. The quickest trip takes 3 hours.
Bus tickets from Lake City to Orlando start at $32.48. For the best rates, it is recommended to book in advance via our app or website. You can pay online using debit or credit cards, or choose to pay in person with cash at selected locations.
To track your bus from Lake City to Orlando, use Greyhound’s bus tracker. This tool provides live updates on the bus’s location and expected arrival times.

Onboard services are subject to availability