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Bus from Midland, TX to Sioux Falls, SD

More travel options

You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Need to make a change?

Easily change your ticket or add bags with Manage My Booking.

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Bus stations and stops in Midland, TX

Please note: your ticket will contain the most up-to-date address information.
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Vehicle passing through a city

Onboard services are subject to availability