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Bus from North Charleston, SC to Jacksonville, FL

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You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.

Reserve a Seat

Reserve your favorite seat when you book your ticket.

Need to make a change?

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Bus stations and stops in North Charleston, SC

Please note: your ticket will contain the most up-to-date address information.

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Frequently asked questions

With Greyhound, you can travel from North Charleston to Jacksonville for as little as $49.98.
The bus route from North Charleston to Jacksonville covers 250 miles.
With Greyhound you can travel from North Charleston to Jacksonville in 5 hours 5 minutes.
To find the next available bus from North Charleston to Jacksonville, just enter your travel date in the search bar above to view departure times and ticket options.
Yes, a bus runs daily from North Charleston to Jacksonville.
You can pay for your bus ticket from North Charleston to Jacksonville using your preferred method — including credit card, PayPal, Google Pay and cash.
You can check the real-time status and location of your bus from North Charleston to Jacksonville using our Bus Tracker.
With Greyhound, you can conveniently reach 44 destinations from Jacksonville, including Orlando, Atlanta, Tallahassee.
If you want to bring your bike with you on Greyhound between North Charleston and Jacksonville, you can. Transport options and prices are subject to availability.
The first bus from North Charleston to Jacksonville departs at 3:15 pm.
The last bus from North Charleston to Jacksonville departs at 3:15 pm.
There is one Greyhound bus stop in North Charleston. You can find its location on the map on this page.
There is one Greyhound bus stop in Jacksonville; Jacksonville (Downtown). You can find its location on the map on this page.

Bus Travel Summary: North Charleston to Jacksonville with Greyhound

  • Travel distance: The bus journey from North Charleston to Jacksonville covers approximately 250 miles, depending on the specific route.
  • Trip duration: The average bus ride with Greyhound from North Charleston to Jacksonville takes around 5 hours 5 minutes, depending on traffic and route conditions.
  • Bus schedule: To view upcoming Greyhound departures, simply enter your travel date and check the next available bus from North Charleston to Jacksonville.
  • Daily bus departures: one bus operates daily between North Charleston and Jacksonville.
  • Greyhound stop in North Charleston: Buses depart from a single location. The stop address is shown above, next to the map.
  • Greyhound stop in Jacksonville: Buses arrive at a single stop. The address is displayed alongside the map above.

Bus Ticket Booking

  • Bus ticket price: Greyhound bus tickets from North Charleston to Jacksonville start at $49.98.
  • Booking: Book your North Charleston to Jacksonville bus ticket online through this website or the free Greyhound app for the best selection and fares.
  • Payment: Choose your preferred payment method from secure options like credit card, PayPal, or Google Pay during checkout.

Seating Options

  • Standard seat: Included at no extra cost and automatically assigned when you book your Greyhound trip from North Charleston to Jacksonville.
  • Seat reservation: Prefer a specific seat or extra legroom? You can reserve one for an additional fee based on the seat type.

Baggage Information

When travelling with Greyhound, your ticket includes 2 pieces of baggage at no extra cost:

  • Carry-on baggage: 1 small bag (up to 25 lb / 12'×7'×16') - must fit under the seat or overhead. Keep valuables with you during your North Charleston–Jacksonville journey.
  • Checked baggage: 1 larger bag (up to 50 lb / 20'×12'×31') - stowed in the luggage compartment before boarding in North Charleston.

Onboard Accessibility with Greyhound

  • Priority seating: Reserved seats are available for passengers with disabilities near the front of the bus.
  • Mobility assistance: Drivers and staff can help with boarding, baggage, and mobility devices - just ask at each stage of your journey.
  • Service animals: ADA-recognised service animals are welcome on board.
  • More info: Full accessibility guidelines are available on our Accessibility Help Page.

Onboard services are subject to availability