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Bus from San Francisco, CA to San Luis Obispo, CA

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You now can select from more schedules across U.S., Mexico and Canada with Greyhound and FlixBus.

Enjoy free onboard Wi-Fi

We offer free Wi-Fi and power outlets to keep you connected and powered up during your trip.

Reserve a Seat

Reserve your favorite seat when you book your ticket.

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Bus stations and stops in San Francisco, CA

Please note: your ticket will contain the most up-to-date address information.

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Frequently asked questions

With Greyhound, you can travel from San Francisco to San Luis Obispo for as little as $42.98. On average, tickets for this route cost around $45.98.
The bus route from San Francisco to San Luis Obispo covers 237 miles.
With Greyhound you can travel from San Francisco to San Luis Obispo in 4 hours 20 minutes.
To find the next available bus from San Francisco to San Luis Obispo, just enter your travel date in the search bar above to view departure times and ticket options.
Yes, there are 2 buses running every day from San Francisco to San Luis Obispo.
You can pay for your bus ticket from San Francisco to San Luis Obispo using your preferred method — including credit card, PayPal, Google Pay and cash.
You can check the real-time status and location of your bus from San Francisco to San Luis Obispo using our Bus Tracker.
With Greyhound, you can conveniently reach 15 destinations from San Luis Obispo, including San Jose, San Francisco, Los Angeles.
If you want to bring your bike with you on Greyhound between San Francisco and San Luis Obispo, you can. Transport options and prices are subject to availability.
The first bus from San Francisco to San Luis Obispo departs at 8:20 am.
The last bus from San Francisco to San Luis Obispo departs at 12:05 pm.
There are 2 Greyhound bus stops in San Francisco. You can find the location of the stops on the map on this page.
There are 3 Greyhound bus stops in San Luis Obispo. You can find the location of the stops on the map on this page.

Bus Travel Summary: San Francisco to San Luis Obispo with Greyhound

  • Travel distance: The bus journey from San Francisco to San Luis Obispo covers approximately 237 miles, depending on the specific route.
  • Trip duration: The average bus ride with Greyhound from San Francisco to San Luis Obispo takes around 4 hours 20 minutes, depending on traffic and route conditions.
  • Bus schedule: To view upcoming Greyhound departures, simply enter your travel date and check the next available bus from San Francisco to San Luis Obispo.
  • Daily bus departures: 2 buses run from San Francisco to San Luis Obispo every day.
  • Greyhound stops in San Francisco: 2 stops are available, including: San Francisco (5th/Townsend), San Francisco Bus Station
  • Greyhound stops in San Luis Obispo: 3 stops are served, including: San Luis Obispo (Cal Poly SLO), San Luis Obispo Railroad Museum, San Luis Obispo Train Station

Bus Ticket Booking

  • Bus ticket price: Greyhound bus tickets from San Francisco to San Luis Obispo start at $42.98 (average fare: $45.98.
  • Booking: Book your San Francisco to San Luis Obispo bus ticket online through this website or the free Greyhound app for the best selection and fares.
  • Payment: Choose your preferred payment method from secure options like credit card, PayPal, or Google Pay during checkout.

Seating Options

  • Standard seat: Included at no extra cost and automatically assigned when you book your Greyhound trip from San Francisco to San Luis Obispo.
  • Seat reservation: Prefer a specific seat or extra legroom? You can reserve one for an additional fee based on the seat type.

Baggage Information

When travelling with Greyhound, your ticket includes 2 pieces of baggage at no extra cost:

  • Carry-on baggage: 1 small bag (up to 25 lb / 12'×7'×16') - must fit under the seat or overhead. Keep valuables with you during your San Francisco–San Luis Obispo journey.
  • Checked baggage: 1 larger bag (up to 50 lb / 20'×12'×31') - stowed in the luggage compartment before boarding in San Francisco.

Onboard Accessibility with Greyhound

  • Priority seating: Reserved seats are available for passengers with disabilities near the front of the bus.
  • Mobility assistance: Drivers and staff can help with boarding, baggage, and mobility devices - just ask at each stage of your journey.
  • Service animals: ADA-recognised service animals are welcome on board.
  • More info: Full accessibility guidelines are available on our Accessibility Help Page.

Onboard services are subject to availability